A diet with high fat content and minimal amount of carbohydrates showed effectiveness in treating heart failure. In mouse, the change of diet gave rather quick results – the disease development was reversed after three weeks. Now scientists want to evaluate the approach for a person.
Researchers from the University of St. Louis have demonstrated the benefits of a ketogenic diet for heart failure, which is caused by metabolic disorders. The disease is caused by myocardial flexibility disorders. New work by scientists shows that keto-acid pyruvate in mitochondria plays a critical role in heart function and the diet can cope with the resulting heart failure.
A change in diet was tested on mouse with heart failure. They were given a diet with high fat content and minimum carbohydrates.
Within three weeks, this allowed them to stop the disease completely and even reverse it.
It is noteworthy that daily fasting also had a positive effect on heart function. After fasting, blood glucose levels decreased, and the concentration of fatty acids and ketone bodies increased.
Presumably, the ketogenic diet stimulates the oxidation of fatty acids, which can have a positive effect on heart function, scientists believe. In their opinion, a keto-diet can be a therapeutic diet for heart failure caused by metabolic disorders, but more research is needed to confirm the results.